University of Idaho University of Idaho
Cells & Evolution of Life


 

 

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University of Idaho
 
Dept. Biological Sciences
 

  CREDITS

Glossary

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P

passive transport
Passive transport mechanisms include diffusion, which is the flow of molecules across the membrane from a region where they are in high concentration to where they are in low concentration. This is accomplished primarily only by small, hydrophobic molecules because the oily core of the phospholipid bilayer poses a barrier to others. An exception is water, in which case the diffusion process is typically referred to as osmosis. In "facilitated diffusion" specialized carrier molecules, such as ion channels, catalyze the passive flow of their substrates across the membrane. Facilitated diffusion of water, for example in the kidneys, occurs via aquaporins.

PEP carboxylase
The enzyme used in C4 and CAM plants to fix CO2 to PEP (phosphoenolpyruvate) to produce a four carbon compound.

peptide linkage
A peptide linkage is a chemical bond formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O). This is a dehydration synthesis (or condensation) reaction and usually occurs between amino acids.  Polypeptides and proteins are chains of amino acids held together by peptide bonds.

peripheral membrane proteins
Proteins associated with membranes, and active on only one side of the membrane.
pH
pH is a measure of the concentration of protons (H+) in a solution and, therefore, its acidity or alkalinity.  It is defined as the negative logarithm of the hydrogen ion concentration.  A pH value greater than 7 is considered basic (or alkaline) while a pH value less than 7 is considered acidic.  A pH value of 7 is considered neutral.
phagocytosis
See Endocytosis

phenotype
The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. Phenotype is determined in large part by genotype, or by the identity of the alleles that an individual carries at one or more positions on the chromosomes. Many phenotypes are determined by multiple genes and influenced by environmental factors. Thus, the identity of one or a few known alleles does not always enable prediction of the phenotype.

Nevertheless, because phenotypes are much easier to observe than genotypes (it doesn't take chemistry or sequencing to determine a person's eye color), classical genetics uses phenotypes to deduce the functions of genes. These inferences can then be checked by breeding experiments. In this way, early geneticists were able to trace inheritance patterns without any knowledge whatsoever of molecular biology.

phosphodiester linkage
Phosphodiester linkages are covalent bonds formed by condensation reactions.  They link together the sugars and phosphate groups of nucleotides to form nucleic acids.

phospholipid
A phospholipid is a lipid whose head contains a positively charged (polar) group that is linked to its two non-polar tails by a negatively charged phosphate group. Both tails consist of a fatty acid, each 14-24 carbon groups long. Phospholipids are the building blocks of biological membranes.

phosphorylation
Phosphorylation is the addition of a phosphate (PO4) group to a protein or a small molecule. Phosphorylation is a tremendously important event.  Many enzymes and receptors are turned on or off by phosphorylation and dephosphorylation. 

ATP, the "high-energy" exchange medium in the cell, is synthesized in the mitochondrion by addition of a third phosphate group to ADP in a process referred to as oxidative phosphorylation. ATP is then used at various points in the series of reactions that constitute glycolysis, to transfer energy to other small molecules. ATP is synthesized at the expense of solar energy by photophosphorylation in the chloroplasts of plant cells.

photoautotrophs
See autotroph
photorespiration
The process by which RuBisCO fixes oxygen, instead of CO2, to RuBP; this is problematic for plants, as no carbon is gained, but energy is expended in order to process the fixation product.
photosynthesis
Photosynthesis is a biochemical process by which the energy of light is converted into chemical energy in plants, algae, and certain bacteria.
photosystem
A conglomeration of pigments in the thylakoid membranes of chloroplasts and photosynthetic prokaryotes that serves to capture light energy; includes the antenna system and reaction center.
pigment
A molecule which differentially absorbs and reflects wavelengths of visible light.
pinocytosis
See Endocytosis
plasmid
Small, circular, self-replicating chromosomes in bacterial cells; plasmids often carry unique genes, such as those involved in antibiotic resistance.
plasmodesmata
Small, membrane-lined channels between adjacent plant cells; important in cell communication and transfer of some nutrients.
pleiotropy
An instance where a single gene affects more than one phenotypic characteristic. Often, the multiple phenotypic characteristics appear unrelated.

ploidy
Ploidy indicates the number of repetitions of the basic number of chromosomes.

A haploid cell bears one set of chromosomes, a diploid cell bears two sets, and a polyploid cell bears many sets.

The ploidy of cells can vary within an organism. In humans, most cells are diploid (containing one set of chromosomes from each parent), though sex cells (sperm and oocytes) are haploid.

Aneuploidy is when a cell contains an abnormal or non-integer ploidy number. This may lead to problems in cell development. Most forms of aneuploidy in humans are lethal, but trisomy (three copies) of the sex chromosome (the cause of Klinefelter's syndrome and others) and of chromosome 21 (the cause of Down syndrome) are relatively common.

Many forms of cancer have incorrect ploidy numbers, due to the accumulation of mutations which increase chromosome missegregation.

polar
Refers to substances that are miscible in water.
polar covalent bond
A polar covalent bond is a covalent bond in which the electron pair is not shared equally between the two atoms.  The more electronegative atom pulls the electrons closer to its nucleus, creating a slight negative charge near that atom.
polarity
A separation of positive and negative charges or tendencies in space.
poly-A tail
A string of adenine residues added to the 3' end of eukaryotic mRNA; poly-A tails likely have a role in transport of mRNA out of the nucleus.
polymer
A large molecule made up of similar or identical subunits called monomers.
polypeptide
Need Definition...
polysaccharide
A macromolecule composed of many monosaccharides (simple sugars). Common examples are cellulose and starch.
polysome
A mRNA molecule associated with several to many ribosomes during the process of translation.
pores
Cellular connections between adjacent cells of fungi.
positive regulation
Control of gene expression whereby a gene that is usually turned off (i.e., not transcribed) is turned on (transcribed) in the presence of a specific inducer. An example of positive regulation is the lac operon of E. coli.

potential energy
Energy that matter possesses because of its location or structure, energy stored that has the potential to do work. Examples: chemical bonds, such as the phosphate bonds of ATP, concentration gradients, height, water backed up behind a dam.

primary active transport
Transport of a substance across a membrane, and against the substance's electrical or chemical gradient; this type of transport requires the direct input of energy, usually acquired from the hydrolysis of ATP.
primary structure
The sequence of amino acids that make up a polypeptide.
prokaryote
Cells (organisms) that do not maintain their DNA in a membrane-bound nucleus; comprises the domains Bacteria and Archaea.
prokaryotic
See prokaryote
prokaryotic chromosome
The circular DNA molecule of prokaryotic organisms, containing the majority of the genes for the cell.
promoter
The regulatory region of genes to which RNA polymerase (and other regulatory proteins in eukaryotic cells) binds.
promoter region
A region of DNA close to a gene or genes that serves to bind RNA polymerase and other regulatory proteins.
prosthetic groups
A small, non-protein molecule attached to an enzyme; some enzymes require prosthetic groups in order to function.
protein
(pro´ teen) [Gr. protos: first] • One of the most fundamental building substances of living organisms. A long-chain polymer of amino acids with twenty different common side chains. Occurs with its polymer chain extended in fibrous proteins, or coiled into a compact macromolecule in enzymes and other globular proteins.

proton
The proton is a subatomic particle with a positive fundamental electric charge of 1.6 × 10-19 coulomb. The nucleus of the most common isotope of the hydrogen atom, H, is a single proton. The nuclei of other atoms are composed of neutrons and protons held together by the strong nuclear force. The number of protons in the nucleus determines the chemical properties of the atom and what chemical element it is.

A proton has a mass of 1.6726231 × 10-27 kg, which is about 1800 times heavier than an electron.

Protons are classified as baryons and are composed of two up quarks and one down quark, which are also held together by the strong nuclear force, mediated by gluons.

Because the electromagnetic force is many orders of magnitude stronger than the gravitational force, the charge on the proton must equal to the charge on the electron, otherwise the net repulsion of having an excess of positive or negative charge (depending on which charge was numerically greater - atoms would not be electrically neutral) would cause a noticeable expansion effect on the universe, and indeed any gravitationally aggregated matter (planets, stars, etc.). It is taken that the positron (antielectron) has the same magnitude charge as the electron but opposite in sign; the same applies for the antiproton and proton.

In chemistry and biochemistry, the term proton may refer to the hydrogen ion in aqueous solution (in other words, the hydronium ion). In this context, a proton donor is an acid and a proton acceptor a base (see acid-base reaction theories).

purines
Nucleotides with a double-ring structure; adenine and guanine.
pyrimidines
Nucleotides with a single-ring structure; thymine, cytosine, and uracil.
pyruvate
One of the twelve key intermediates; a three carbon molecule found in the pathways of photosynthesis and respiration.
pyruvate oxidation
The stage of aerobic respiration during which pyruvate is oxidized to acetate, which is subsequently linked to coenzyme A to form acetyl-CoA.