Lecture 6 - Absorption of Toxicants
See Lecture Schedulefor Delivery Date
Learning Objectives
- Describe the ways in which toxicants interact with cells.
- Recognize how the molecular characteristics of toxicants affect entrance into a cell.
- Explain human anatomy as related to integumentary, respiratory, and digestive systems.
- Summarize routes of toxicant absorption.
Advance Reading
- Richards 2nd ed., pp 129-144
- NLM Toxicology Tutor Absorption
- Case Study: Aldicarb in Watermelons
Resources
Keywords
- Absorption
- Active transport
- Adenosine triphosphate (atp)
- Alveolar region
- Cell membrane
- Concentration gradient
- Digestive system
- Endocytosis
- Epithelial cells
- Epithelium
- Exocytosis
- Facilitated diffusion
- Hydrophilic
- Hydrophobic
- Integumentary system
- Lipid soluble
- Lipophilic
- Minute volume respiration (mvr)
- Mucociliary escalator
- Nasopharyngeal region
- Nonpolar
- Occluding cell junctions
- Overton’s rules
- Partition coefficient
- Percutaneous
- Phagocytosis
- Phospholipid
- Phospholipid bilayer
- Pinocytosis
- Pneumocytes
- Poiseuille’s Law
- Polar molecules
- Repiratory system
- Semipermeable membrane
- Simple diffusion
- Tracheobronchial region
Suggested Reading
None
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