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Lecture 6 - Absorption of Toxicants

Learning Objectives

  1. Describe the ways in which toxicants interact with cells.
  2. Recognize how the molecular characteristics of toxicants affect entrance into a cell.
  3. Explain human anatomy as related to integumentary, respiratory, and digestive systems.
  4. Summarize routes of toxicant absorption.
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Advance Reading

  1. Shibamoto & Bjeldanes, pp 12-19
  2. Hughes, pp 45-57
  3. NLM Toxicology Tutor Absorption

Suggested Reading

  1. What happened in Bhopal?

Resources

Keywords

  • Absorption
  • Active transport
  • Adenosine triphosphate (atp)
  • Alveolar region
  • Cell membrane
  • Concentration gradient
  • Digestive system
  • Endocytosis
  • Epithelial cells
  • Epithelium
  • Exocytosis
  • Facilitated diffusion
  • Hydrophilic
  • Hydrophobic
  • Integumentary system
  • Lipid soluble
  • Lipophilic
  • Minute volume respiration (mvr)
  • Mucociliary escalator
  • Nasopharyngeal region
  • Nonpolar
  • Occluding cell junctions
  • Overton’s rules
  • Partition coefficient
  • Percutaneous
  • Phagocytosis
  • Phospholipid
  • Phospholipid bilayer
  • Pinocytosis
  • Pneumocytes
  • Poiseuille’s Law
  • Polar molecules
  • Repiratory system
  • Semipermeable membrane
  • Simple diffusion
  • Tracheobronchial region