University of Idaho

Research Team

Patrick J. Hrdlicka
Assistant Professor

Poster Award - Michael E Østergaard and coworkers, won the poster award in the Graduate Student category at the Donald S. Matteson symposium held at WSU early October 2009.

NIH EUREKA R01 Funding - Dr. Hrdlicka and co-PIs Dr. Madhusudhan R. Papasani and Prof. Rod A. Hill (both Animal and Veterinary Science) have secured a highly competitive three-year R01 award from the National Institutes of Health (NIH) EUREKA (Exceptional, Unconventional Research Enabling Knowledge Acceleration) program to study novel gene knockdown agents termed Invader LNAs. A press release can be found here.

Teaching (Fall 2009)– PJH teaches CHEM277 Organic Chemistry I.

Publication (2009) - Our manuscript outlining novel functionalized LNA as efficient DNA-binders using the triplex approach has been accepted for publication in Chemical Communications.

Publication (2009) - Our manuscript outlining the use of C5-functionalized LNAs for efficient RNA targeting has been published in ChemBioChem.

Publication (2009) - A manuscript outlining the development of PNA-based biosensors has been published in Analytical Letters. This effort was spearheaded by the Maki group at the Univ. Idaho Research Park in Post Falls.

Publication (2009) - Our manuscript describing a concise synthetic route to isotopically labeled ribonucleosides has been published in Tetrahedron Letters.

Publication (2009) - A review on "1-Dimensional Silica Structures and Their Applications to the Biological Sciences" was prepared jointly by the BANTech team and has been published in “Nanomaterials for the Life Sciences, Nanostructured Oxides” (Wiley 2009).

Publication (2009) - Our manuscript describing recognition of RNA strands in parallel orientation using beta-L-LNA has been published in Bioorganic Medicinal Chemistry Letters.

Publication (2009) - Our manuscript describing a novel synthetic methodology to facilitate selective deacylations of peracylated ribonucleosides has been published in Tetrahedron Letters.

Publication (2009) - Our manuscript describing the use of intercalator-functionalized LNA for DNA targeting has been published in Journal of Organic Chemistry 2009, 1070-1081.

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