Hrdlicka Laboratory - Nucleic Acid Chemistry

Patrick J. Hrdlicka

 

PO Box 442343

Renfrew Hall 329

Moscow, Idaho 83844-2343

United States of America

 

Phone: +1 208-885-0108

Fax: +1 208-885-6173

Email: hrdlicka@uidaho.edu

Contact:

Patrick J. Hrdlicka

Assistant Professor

 

Welcome to the Hrdlicka lab webpage

 

You need Internet Explorer running from

a PC to view this webpage

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research team (April 2008)

News

· Publication - A NAC-driven multi-author manuscript on ‘Chemically Modified Oligonucleotides with Retained RNaseH Response’ has been published in Bioorganic and Medicinal Chemistry Letters 2008, 2296-2300.

· 4xPublications - Research papers outlining our recent collaborative efforts with Prof. Wengels group at the Nucleic Acid Center, have recently been published in Nucleosides Nucleotides Nucleic Acids 2007, 26, 1261/1403/1407/1415.

· Funding - PJH has been awarded his second UI Seed Grant, this time to conduct studies on biosensors using functionalized nucleic acids.

· 2xFunding - Idaho NSF EPSCoR Research Infrastructure Improvement (RII) will support our project on labeled nucleic acids. Funding was also granted to purchase a Karl-Fisher Titrator to determine water level in solvents.

· Presentations - PJH presented “N2’-Functionalized 2’-Amino-a-L-LNA: A Novel Class of Locked Nucleic Acids as Emerging Tools for Nucleic Acid Therapeutics and Diagnostics” at the 2008 Spring American Chemical Society Meeting in New Orleans, USA. Furthermore, Michael E. Østergaard presented a poster on our recent results on functionalized LNAs as versatile diagnostic tools.

· Teaching - PJH is teaching 472/572 “Rational Design of Pharmaceuticals” this semester.

· Teaching – PJH will be teaching 571 “Current Topics in Organic Chemistry” in Fall 2008. The topic will be Nucleic Acids: Synthesis and Applications in Therapeutics, Diagnostics and Nanoscience.

· Student award - Michael E. Østergaard, has been awarded the UI COGS Doctoral Scholarship to conduct studies on biosensors.

· Student award - Brooke Andersen, undergraduate researcher in our team, has been awarded the 2008 Senator Larry E. Craig Endowment Scholarship to participate in the 2008 ACS Spring meeting.

· 2xSupport - Michael E. Østergaard and Brooke Anderson have received financial support from the Student Grant Program and a Hill Research Foundation, respectively.

· More “news” in the archives