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Lecture 20 - Naturally Occurring Toxicants as Etiologic Agents of Foodborne Disease

Learning Objectives

  1. Examine the etiology (causation) of human disease related to naturally-occurring foodborne toxicants.
  2. Understand the chemical complexity of foods.
  3. Explore goiter, tropical ataxia neuropathy (TAN), tropical amblyopia, lathyrism, and their linkage to foodborne toxicants.
  4. Review a range of natural food toxicants that are involved in human disease.

LECTURE MATERIALS

Slides

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Lecture Outlines (PDF)

LECTURE ACTIVITIES

Homework

Discussion

FoodTox Lecture20 from Professor Greg Möller on Vimeo.

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Advance Reading

  1. Shibamoto & Bjeldanes, pp 124-143

Suggested Reading

  1. What is G6PD Deficiency? G-6-PD Deficiency Association
  2. Plant Toxins: Lathyrism
  3. Plant Toxins: Konzo
  4. Acetylcholine and Synaptic Receptor Toxins
  5. Plant Toxins: Ricin
  6. Plant Toxins: Veno-occlusive Disease
  7. Plant Toxins: Cardiac Glycosides

Resources

Keywords

  • Goiter
  • Tropical ataxia neuropathy (TAN)
  • Tropical amblyopia
  • Lathyrism
  • Goitrogens
  • Cyanogenic glycosides
  • Lectins
  • Alkaloids
  • Protease inhibitors
  • Vasoactive amines
  • Osteolathyrism
  • Neurolathyrism
  • Beta-L-glutamylaminoproprionitrile
  • B-N-oxalyl-L-alpha,B-diaminoproprionic acid


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