## Math 563 (Mathematical Genetics). Fall 2021

**UI Instructor:**
Steve Krone
**Office:** 421 Brink Hall

**Office Hours:** by appointment.

**WSU Instructor:**
Dick Gomulkeiwicz

**Office:** 391 Eastlick; 509-335-2527

**Office Hours:** by appointment.

**Class Time:** Mondays WSU ADBF 1002

Wednesdays 5:10 - 6:20, UI TLC 047

**Prerequisite:** some knowledge of probability
**Text:** John H. Gillespie, *Population Genetics: A Concise Guide*, 2nd ed.

This is a graduate course on population genetics. The first half of the
course will be based on readings from the text and instructor-led discussion.
The second half will be more lecture-based and focuses on coalescent theory.
The material on coalescent theory will come from several sources, including
Wakeley's Coalescent Theory, Hein, Schierp and Wiuf's Gene Genealogies,
Variation and Evolution, and some notes by Paul Joyce.
The last few weeks of the course will be dedicated to student presentations of
research in population genetics (typically from the literature). There will be
regular homework assignments. Grades will be based on HW, presentations, and active
class participation.

Syllabus

Schedule

**Homework:**

HW 1

HW 2

**Resources:**

Gillespie book, 1st ed.

Gillespie book (ch 4), 2nd ed.

Geometric Growth model

Wright-Fisher model

Some coalescent theory notes

Meiotic drive calculations

Lethal gene drive calculations

Gene drive review paper