| Introduction:
Opiates are substances that have been used thousands of years for a
variety of purposes including diarrhea and inducing sleep. More
recently, they have been used for pain relief (including psychological pain)
and most recently, euphoria. These drugs develop rapid tolerance and
dependence. In addition, a popular route of delivery for opiates has
been injection. As a result of needle sharing,
injection use has significantly increased the prevalence of HIV, Hepatitis,
and other STDs among users and the individuals they participate in sexual
activities with. This section reviews a variety of opiates, side effects
and how they work.
Outcomes:
After completing this lesson you should:
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Understand
the concept of pain, and how opiates work.
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Understand some history of opioid use
and terms associated with opioid use.
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Differentiate
between different types of receptors associated with
opioid use and the behavioral effects these receptors exert when
occupied by opiate
compounds.
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Understand the
different types of opiates and the effects they exert.
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KSA’s
3.
Describe the behavioral, psychological, physical health and
social effects of psychoactive drugs including alcohol and tobacco on the
consumer and significant others.
4.
Recognize the potential for substance use disorders to mimic a
variety of medical and psychological disorders and the potential for medical
and psychological disorders to co-exist with addiction and substance abuse.
5. Be familiar with medical
and pharmaceutical resources in
the treatment of addictive diseases and other
substance-related disorders.
102. Describe warning signs, symptoms, and the
course of substance use disorders.
Some Objectives:
| This section is designed to provide
you with information about
the varieties of opiates,
drug use and its impact on high-risk
behavior. It also will discuss
how opiates impact
a variety of receptors and the behavioral effects that occur. |
Some Important Terms:
| Opioid, Opiate |
| Analgesia |
| Mu, Kappa, Delta, Nociception receptors |
| Endorphins |
| Tolerance, dependence, cross tolerance |
| Pure, Partial, and Mixed agonists and antagonists |
| Medial Forebrain Bundle. |
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